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Oxycodone is a short-acting opioid. Oxycodone relieves pain for about fourto six hours, so it needs to be given 4 to 6 times a day to provide pain relieffor the whole day. Oxycodone worksby binding to specific receptors in the brain known as opioid receptors. Themedicine is relatively selective for a type of opioid receptor, that is, themu-opioid receptor.

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Oxycodone is a complete agonist at the mureceptor, meaning that it does not have a ceiling effect for pain relief. Therisk of side effects, like CNS and respiratory depression, rises with higherdoses, and the chances of overdosage increase.